Welcome to MouseMet
The integrated suite of nociceptive tests for mice and rats
MouseMet EvF now has double the sensitivity... at half the price!
Our unique, rotary action instrument for mechanical thresholds on mice now measures down to 0.05g
And is priced at £990
And RatMet EvF (1-80g), for nociceptive thresholds on larger rodents, is the same price. These prices are ex-works, for payment by credit card. Please fill in the contact form at the foot of the page and I'll send you a quote for shipping, and then a payment link.
Whether you are measuring hypoalgesia or hyperalgesia, MouseMet is designed to make your behavioural testing easy; with the elbows supported on the bench, the tip is brought into contact and the force applied by rotating the handles. At the nociceptive threshold, the tip is removed and the green button pressed to record the test. And with a starting force of just 0.05g, the chance of a "touch-on" paw withdrawal (from the contact of the probe rather than a true mechanical threshold) is even lower than before.
MouseMet EvF is supplied with 2 probes and a calibration arm. We have always taken continuity of data very seriously, so the calibration arm also allows you to compare your existing von frey filaments directly with MouseMet.
MouseMet EvF is often bought in conjunction with our hot probe This offers advantages over the "Hargreaves" or hot plate test as our hot probe is used in the same runs as our EvF. So you can halve the acclimation time and reduce the stress for the mice. The hot probe has exactly the same rotary action as the EvF but with a 2mm thermal probe on the end of the rotating arm. It is brought into contact with a force of under 1g (again to avoid touch-on responses) and heating starts and stops automatically. And, to complete the set, we also offer a cold probe with the same footprint.
shows cooling of mousemet probe after preheat to skin temperature
shows force rise of mousemet probe
shows probe heating to thermal threshold
shows cooling of mousemet probe after preheat to skin temperature
All stimullii are applied automatically and the threshold recorded on removal. And all three, EvF, Hot and Cold can be used in the same mouse runs.
This vastly reduces acclimation time and stress for the mice: a big contribution to the 3Rs
"MouseMet EvF provided our behavioural endpoint to quantify tactile allodynia and its attenuation in this mouse CIN model. It is a terrific piece of instrumentation that has lead us to a novel approach for treating CIN"
Dr K Sufka
Professor of Psychology and Pharmacology
University of Mississippi
ABOUT TOPCAT METROLOGY LTD
Topcat Metrology develops and supplies novel measurement equipment for veterinary research. The company's original product, developed twenty years ago, was a thermal threshold testing system. The product range today now includes mechanical threshold testers, remote-controlled systems (allowing completely free-ranging subjects during a test) and hand-held mechanical testers, suitable for clinical use.
GET IN TOUCH
Gravel Head Farm, Downham Common
Little Downham, Ely
CAMBS UK
+44 7739 913696